Our goal is to better understand the molecular basis of these diseases to improve diagnosis and develop new strategies for better clinical treatments for patients and their families.

Brent Fogel, M.D., Ph.D. is the only clinician-scientist in the world researching new ways to treat AOA2.

Dr. Brent Fogel is the Director of the UCLA Neurogenetics Clinic and a member of the UCLA Ataxia Center. He is leading a multi-year research study to develop a groundbreaking gene therapy that has the potential to stop the progression of this disease.  

Please join three brothers on a quest to discover a cure for ataxia, the worst disease you have NEVER heard of, by donating today. 

Ataxia with Oculomotor Apraxia Type 2 (AOA2) is a rare neurological disease. For families, such as ours, who are affected by it, life is never the same. Unfortunately, AOA2 tends to begin in late adolescence, leaving kids unable to drive, walk, write, and handle their own basic daily needs. Common symptoms include balance problems, tremors, loss of motor skills, double vision, and muscle weakness.

We remain optimistic about the future, thanks to Brent Fogel, M.D., Ph.D. who is determined to find a cure. He is the only clinician-scientist in the world researching new ways to treat AOA2.

Dr. Brent Fogel is the Director of the UCLA Neurogenetics Clinic and a member of the UCLA Ataxia Center. He is leading a multi-year research study to develop a groundbreaking gene therapy that has the potential to stop the progression of this disease.  

Your financial support is critical, as this research is only funded by philanthropic support. 

Thank you for your generosity! Every dollar makes a difference.

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To donate by check via USPS, please issue a check payable to The UCLA Foundation with note/memo stating it is to support the De Mint AOA2 Research Fund (62741C). Please mail the check to The UCLA Foundation, PO Box 7145, Pasadena, CA 91109-9903. 

About Our Fogel Lab

The Fogel Lab seeks to understand the basic and fundamental molecular mechanisms underlying human neurodevelopment and neurodegenerative disease. Under the direction of the Principal Investigator Dr. Brent Fogel, we are currently examining how specific genes and genetic pathways influence the pathogenesis of neurogenetic diseases, including cerebellar ataxia, other neurodegenerative disorders, and neurodevelopmental conditions. Our goal is to better understand the molecular basis of these diseases to improve diagnosis and develop new strategies for better clinical treatments for patients and their families.